US Patent 7,442,773. Universal peptide-binding scaffolds and protein chips. Inventors: Huimin Zhao; Olga Esteban. Assignee: The Board of Trustees of the University of Illinois
The scaffold is used to bind a target, which can be a peptide or peptides of interest , or peptides representing the entire proteome. The target can be protein fragments prepared by enzymatic digestion of the whole proteome or N- or C-terminal short sequences exposed by chemical denaturation of the entire proteome.


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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.

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