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US Patent 7,105,339. Retentate chromatography and protein chip arrays with application in biology and medicine. Inventors: T. William Hutchens; Tai-Tung Yip. Assignee: Ciphergen Biosystems
Inventors discovered methods of retentate chromatography for resolving analytes in a sample involving “adsorbing the analytes to a substrate under a plurality of different selectivity conditions and detecting the analytes retained on the substrate by desorption spectrometry,” according to the patent’s abstract.

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