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Recent Patents of Interest in Proteomics: Apr 26, 2007

US Patent 7,208,573. Enrichment of phosphate peptides for proteomic analysis. Inventor: Karla Robotti. Assignee: Agilent Technologies
Invention pertains to a method for separating phosphorylated peptides from a mixture of phosphorylated and unphosphoryated peptides. A kit is included in the invention. According to the abstract, a collection of peptides, some with one or more phosphate groups, is reacted with a first resin. They are then reacted with a capture ligand, which reacts with the phosphate group of the phosphorylated peptides to form a bond. Phosphorylated peptides are separated from unphosphorylated peptides with the capture ligand.

 US Patent 7,208,268. Differential phage capture proteomics. Inventor: Paul Stroobant. Assignee: Not available
Invention pertains to methods of identifying, isolating, and capturing proteins and other biomolecules “differing between two complex biological samples using affinity chromatography and phage display techniques,” according to the abstract.

US Patent 7,202,471. Method and apparatus for mass spectrometry. Inventors: Toshinobu Hondo; Jun Tamura. Assignee: JEOL
The method starts with gaining a total ion chromatogram via mass spectrometry. A desired mass peak from the displayed accumulation mass spectrum is chosen. “Another mass chromatogram coincident in elution start time, maximum elution time, and elution end time with the mass chromatogram of the selected mass peak are extracted and selected out as a mass peak,” according to the abstract, and a mass spectrum of a single component is reconstructed.

US Patent 7,202,358. Methods for producing ligand arrays. Inventor: John Hargreaves. Assignee: Not available
Invention pertains to methods of producing ligand arrays, including those with proteomic applications.

US Patent 7,202,093. Method for labeling phosphorylated peptides, method for selectively adsorbing phosphorylated peptides, complex compounds used in the methods, process for producing the complex compounds, and raw material compounds for the complex compounds. Inventors: Tohru Koike; Akihiko Kawasaki; Tatsuhiro Kabashi; Makoto Takahagi. Assignee: Kabushiki Kaisha Nard Kenkyusho
Invention pertains to a method for detecting phosphorylated peptides in samples derived from living organisms, a method for selectively adsorbing the phosphorylated peptides, and compounds that are highly coordinated to the phosphorylated peptides and useable in the methods.

US Patent 7,202,076. Label-free high-throughput optical technique for detecting biomolecular interactions. Inventors: Brian Cunningham; Jane Pepper. Assignee: SRU Biosystems
Invention pertains to methods and compositions for detecting biomolecular interactions. Labels are not required and the methods can be performed in high throughput

The Scan

Not Yet a Permanent One

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Unfair Targeting

Technology Review writes that a new report says the US has been unfairly targeting Chinese and Chinese-American individuals in economic espionage cases.

Limited Rapid Testing

The New York Times wonders why rapid tests for COVID-19 are not widely available in the US.

Genome Research Papers on IPAFinder, Structural Variant Expression Effects, Single-Cell RNA-Seq Markers

In Genome Research this week: IPAFinder method to detect intronic polyadenylation, influence of structural variants on gene expression, and more.