Biomarkers crashed back to Earth this week as clinicians and regulatory specialists joined the usual crowd of academics and industry scientists for a sobering reality check at the IBC Biomarkers conference in Reston, Va. Speakers across the board warned of steep obstacles to bringing a validated, reproducible, effective, and FDA-approved proteomic biomarker test — diagnostic or otherwise — to the clinic, as they hashed out the nitty gritty details of sample collection and handling, statistical analysis, identification of spectrum peaks, and government regulations.

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The London School of Economics' Daniele Fanelli argues at the Proceedings of the National Academy of Sciences that the reproducibility crisis in science isn't as dire as some say.

A team of researchers in Portugal has examined the genomic basis for racing pigeons' athleticism and navigational skills, finding it's likely polygenic.

Wired reports that diagnostic firms continue to seek, post-Theranos, the ability to diagnose diseases from small amounts of blood.

In Science this week: analysis of DNA from ancient North Africans, and more.