US Patent No. 6,756,586. Methods and apparatus for analyzing biological samples by mass spectrometry. Inventor: Richard Caprioli. Assignee: Vanderbilt University.
Covers methods and apparatuses for analyzing proteins and other molecules within a sample. A specimen is struck with laser beams so that it releases proteins, and the atomic mass range is measured. The atomic mass range is analyzed to determine the spatial arrangement of the proteins in the sample and the proteins are identified as a function of the arrangement.