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Researchers in Spain and the UK have used mass spectrometric analysis to demonstrate in vivo that the uterine environment can change in the presence of gametes.
 
While such changes had previously been shown in vitro, the work, performed in the porcine reproductive system, is the first to report and demonstrate changes in oviductal protein secretion in living mammals in response to the presence of sperm and oocytes in the oviduct at the time of ovulation, the researchers said.
 

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