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Promega, AnaSpec

Promega this week launched the ProteasMAX Surfactant for the enhancement of enzymatic performance of trypsin and other proteases in preparation for analysis by mass spectrometry or liquid chromatography.
ProteasMAX allow researchers to obtain a more complete digestion prior to protein analysis resulting in more accurate data in shorter time and reduced risk of sample degradation, Promega said in a statement. It is compatible with existing protocols of 1D and 2D in-gel digestion of a purified protein or the digestion of complex protein samples by 2D LC-MS/MS.

AnaSpec last week introduced ClearPoint Peptides, heavy isotope-labeled peptides for the absolute quantitation of proteins.
ClearPoint peptides offer a choice of heavy hydrogen, carbon, or nitrogen istopes specifically labeled at single, multiple, or universal positions.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.