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Prolinx, Biomax Human Genome Database, FGENESH++ , Pedant-Pro


Prolinx has released new versions of its Versalinx chemical affinity technology for isolating proteins from complex samples. Specifically, the company said its Versalinx product now allows researchers to customize the purification of molecules by building affinity columns under mild conditions suitable for preserving biological activity. In addition, the Versalinx product includes pre-conjugated ligands that reduce the time required for optimizing affinity isolation experiments.

Biomax Informatics has made its manually-annotated human genome database, the Biomax Human Genome Database, available for license, the Martinsried, Germany-based company said last week. The database contains both automatic annotation and extensive manual annotation by Biomax scientists. The genes were identified with the FGENESH++ gene modeling software, licensed from Softberry, and automatic annotation to identify putative protein structure and function, was performed using Biomax''s Pedant-Pro sequence analysis software suite. Further information is available at

The Scan

Study Examines Insights Gained by Adjunct Trio RNA Sequencing in Complex Pediatric Disease Cases

Researchers in AJHG explore the diagnostic utility of adding parent-child RNA-seq to genome sequencing in dozens of families with complex, undiagnosed genetic disease.

Clinical Genomic Lab Survey Looks at Workforce Needs

Investigators use a survey approach in Genetics in Medicine Open to assess technologist applications, retention, and workforce gaps at molecular genetics and clinical cytogenetics labs in the US.

Study Considers Gene Regulatory Features Available by Sequence-Based Modeling

Investigators in Genome Biology set sequence-based models against observational and perturbation assay data, finding distal enhancer models lag behind promoter predictions.

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.