A team led by researchers at Princeton University has built a global protein interaction network for all 11 human histone deacetylases.

The project, representing the most comprehensive characterization to date of the HDAC interactome, identified more than 200 previously unreported interactions, and offer "an important resource for elucidating HDAC functions in health and disease," Princeton researcher Ileana Cristea, leader of the effort, told ProteoMonitor.

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