The following companies released new products with proteomics applications at PITTCON 2005: Agilent Technologies, Beckman Coulter, Bio-Rad, Bruker BioSciences, Shimadzu, Thermo Electron and Waters. For a list of the new products and brief descriptions, see p. 3.
The Blueprint Initiative announced this week the release of a new version of its Biomolecular Interaction Network Database, called BIND v3.7. New features of the updated version include OntoGlyph summaries, which provide researchers with a rapid view of what functional, binding, and subcellular localization features are associated with their query molecule; OntoGlyph search filtering, which allows researchers to focus their attention on molecules that fit within specific categories; tabbed search results, which are divided into interaction, complex, and pathway categories; and a BIND downloads interface, which makes it easier for users to access and download files from the BIND FTP site.
KPL released last week two new chemiluminescent substrates for rapid detection of alkaline phosphatase conjugates on membranes. PhosphaGLO Reserve AP Substrate allows for visualization of protein at fentogram concentrations, while conserving primary antibody, the company said. PhosphaGLO AP Substrate allows for routine detection of proteins in the pictogram range. Both products feature sustained light emission for up to five days, allowing for detection over an extended time period.
GWC Technologies recently launched its SPRimager II detection system. Instead of using bulky fluorescent labeling tags, the product achieves detection using Surface Plasma Resonance. It allows for label-free analysis of protein and other molecular arrays. It may also be used to monitor protein-protein interactions, as well as other interactions involving DNA, RNA, carbohydrates and ligands.
GE Healthcare launched this week two new chromatography media for the industrial purification of monoclonal antibodies. According to the company, MabSelect Xtra is a recombinant protein A-based medium engineered to give 30 percent higher dynamic binding capacity than other commercially available protein-A based media. MabSelect SuRe is a chromatography medium based on an alkali-stabilized protein-A derived ligand that is engineered to provide greater stability than conventional protein A-based media in the alkaline conditions used in cleaning-in-place protocols.