PerkinElmer introduced three new products with proteomic and protein analysis applications at the Human Proteome Organization World Congress this week. The products are the company’s first reagents for proteomic research, a PerkinElmer official said.
The ExacTag mass tags, a family of thiol and amine reactive isobaric mass tags, allow for the quantification of protein expression of up to 10 samples simultaneously. The tags enable analysis of protein expression pharmacodynamics.
Phos-tools, including the Phos-trap and Phos-tag, enrich and detect protein phosphorylation, provide high binding selectivity for phosphorylated tyrosine, serine, and threonine residues. The tools are intended for studying phosphorylation cascades triggered by kinases and phosphatases.
Affinity-tools offer a selection of protein enrichment and detection kits. The technology allows researchers to selectively isolate proteins and detection by gel resolution and mass spectrometry. They have been designed with elution buffers compatible with all mass spectrometry ionization sources, the company said.
Also at HUPO, Alfa Wasserman Proteomic Technologies launched its AW Promatix 1000 in the US, its first tool specifically for proteomic research. It also launched the new MitoID Kit for the visualization and detection of mitochondria using the Promatix 1000.
The Promatix 1000 is a continuous-flow ultracentrifugation system employing buoyant density accumulation to automate the separation, fractionation, and enrichment of sub-cellular particles in a single step. Organelles, organellar subtypes, and macromolecular complexes are separated according to the buoyant density in the gradient.
The instrument sells for about $175,000, said an Alfa Wasserman official. The company plans to launch the instrument in Europe next year.
The MitoID Kit includes a combination of five mitochondrial-specific and formulated antibody controls, and protocols for Promatix 1000 analysis from samples of up to five Western blot experiments. Six different kits are available for mitochondrial analysis of brain, liver, or heart tissue for rat or mouse models.
Bruker Daltonics launched its ClinProt MB-LAC LCA-Lens Culinaris glycoprotein kit at HUPO this week. The new LCA magnetic beads complement Bruker’s portfolio of ClinProt glycobeads, the company said in a statement.
Agilent this week launched the 1200 Series diode-array and multiple-wavelength liquick chromatography detectors. The instruments have radio frequency identification tags for flow cells and record parameters such as product and serial number, production date, cell dimensions, lifetime and usage of a UV lamp added to provide data traceability, the company said in a statement.