A team led by researchers at Toronto's Mount Sinai Hospital has completed a proteomic analysis of the scaffold protein Shc1 and its role in regulating EGF signaling.

The study, published this week in Nature, offers insights into the processes and protein interactions through which Shc1 modulates EGF network activity. It also provides a demonstration of targeted proteomics' potential as a tool for unraveling complex cellular processes.

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