Skip to main content
Premium Trial:

Request an Annual Quote

OriGene, Institute for Systems Biology in Database Alliance

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – OriGene Technologies and the Institute for Systems Biology today said that they will collaborate in the creation of a proteotypic PeptideAtlas and a mass spectrometry standard database for 5,000 human proteins.

The alliance will apply ISB's systems biology mass spec expertise to OriGene's collection of full-length human proteins, the partners said in a statement. They said that creation of the atlas and the SRM/MRM (single reaction monitoring, multiple reaction monitoring) mass spec database will enable quantitative protein analysis and facilitate lab-to-lab data validation.

"The field of proteomics combined with systems biology will push discovery further, but it is essential to validate these discoveries with a large scale mass spectrometry standard database," Leroy Hood, president and co-founder of Seattle-based ISB, said in a statement. "By providing ISB with access to one of the largest collections of full-length human protein in the world, this collaboration will rapidly accelerate the validation of ISB's discoveries."

Further terms of the alliance were not disclosed.

In addition to its collection of more than 5,000 purified human proteins, Rockville, Md.-based OriGene also claims to have the world's largest cDNA and shRNA clone collections, 100,000 validated human tissues, and assay products based on Luminex's multiplex technology.

The Scan

Study Finds Sorghum Genetic Loci Influencing Composition, Function of Human Gut Microbes

Focusing on microbes found in the human gut microbiome, researchers in Nature Communications identified 10 sorghum loci that appear to influence the microbial taxa or microbial metabolite features.

Treatment Costs May Not Coincide With R&D Investment, Study Suggests

Researchers in JAMA Network Open did not find an association between ultimate treatment costs and investments in a drug when they analyzed available data on 60 approved drugs.

Sleep-Related Variants Show Low Penetrance in Large Population Analysis

A limited number of variants had documented sleep effects in an investigation in PLOS Genetics of 10 genes with reported sleep ties in nearly 192,000 participants in four population studies.

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.