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Nonlinear Dynamics, Genedata, Geneva Bioinformatics, GenoLogics, Rolf Apweiler, David Onions, Thomas Ingolia, Ian Humphery-Smith, and BioSystems International


New Products

Nonlinear Dynamics is planning to launch its Tiger Technology for the pixel-by-pixel warping of two-dimensional gel images this fall, according to John Spreadbury, group sales and marketing director of Nonlinear Dynamics and CEO of Nonlinear USA.

While most other 2D-gel-analysis technologies detect spots and then compare them, Nonlinear's Tiger Technology uses pixel technology without comparing spots, Spreadbury told ProteoMonitor. The warping technology allows for the alignment of gels without gel editing, which allows for the easy comparison of images. About 20 images could be compared in one day, Spreadbury said.

Nonlinear Dynamics released this week a new Progenesis range of products for the analysis of 2D electrophoresis gels. The company also announced that it is developing its modas platform for bringing together data from multiple applications, sources and disciplines.

The modas platform will ultimately be able to incorporate data from 1D and 2D gels, mass specs and arrays into one system, the company said.

Genedata announced this week the expansion of its Expressionist software product to integrate mass spectrometry analysis with its combined -omics data analysis platform. The expanded platform supports analysis of gel-free proteomic and metabolomics technologies. The tools are able to load raw spectrographic signals as input.

Geneva Bioinformatics announced this week the latest release of its protein identification platform, Phenyx. The new release incorporates the Phenyx Web Interface, a new Web-based client used to interact with the Phenyx calculation engine. Phenyx is now directly accessible via a Web browser.

The web interface introduces a number of new platform features, which include a Protein Details View which displays an extensive interpretation of a specific protein, Excel and XML reports of complete jobs, and a configurable management console that allows users to define their own amino acid modifications and enzymatic cleavage rules.

GenoLogics announced this week the launch of OmixLIMS, a software platform for systems biology research. According to GenoLogics, OmixLIMS gives laboratories focused on proteomics, genomics, transcriptomics and metabolomics the ability to implement a lab information and scientific data management system on a common platform, facilitating experimental workflow management, and scientific data integration, sharing and analysis.

Movers & Shakers

Rolf Apweiler has been elected to become the next president of the Human Proteome Organization (seeIndustry Briefs). In addition, Catherine Fenselau and Young-Ki Paik have been elected to become the next vice presidents of HUPO.

David Onions has been promoted to chief medical officer of Invitrogen, a new position, the company said this week. He used to be chief scientific officer for BioReliance, a company Invitrogen acquired in 2004. As CMO, Onions will be responsible for guiding Invitrogen's scientific efforts as it moves into areas more closely associated with medical research and closer to patients. He is also a personal chair in veterinary molecular virology at the University of Glasgow. Onions holds a PhD from the University of Cambridge and a BVSc from Bristol University.

Thomas Ingolia has become chief executive officer of Medisyn Technologies, the Minnetonka, Minn.-based company said today. He joins Medisyn from Prolexys Pharmaceuticals, formerly Myriad Proteomics, where he was CEO. Ingolia holds a PhD in biochemistry from the University of California, Berkeley.

Ian Humphery-Smith has been chief executive officer of the Biosystems Informatics Institute and its commercial trading arm, Turbinia , both of Newcastle-upon-Tyne, UK , since last December, GenomeWeb News has learned. Since he left his post as COO of Glaucus Proteomics, which went out of business three years ago, he has been a consultant to the biotechnology industry. Humphery-Smith holds a PhD and a BSc in parasitology and infectious diseases from the University of Queensland, Australia.

BioSystems International has appointed a scientific advisory board, the Evry, France-based biomarker company said last week. Members of the board are Laszlo Fesus of the University of Debrecen Medical and Health Science Center in Hungary; Andras Guttman of the University of Innsbruck, Austria; William Hancock of Northeastern University; Barry Karger of Northeastern University; Edward Rubin of Lawrence Berkeley National Laboratory Berkeley; Laszlo Takacs, president and CSO of BioSystems International; Jean Paul Thiery of the Institut Curie in Paris; and Peter Zavodszky of Eotvos Lorand University in Budapest.

The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.