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NIH, EMD Biosciences, The Automation Partnership, Molecular Connections, United Bioinformatica, Tienta Sciences, Jobin Yvon-Horiba


NIH Flags $2.5M for Genomics and Proteomics of Premature Babies

The National Institute of Child Health and Human Development released a Request for Applications last week that commits $2.5 million in fiscal year 2005 to genomic and proteomic research into premature birth.

The aim is to create a network for premature birth research, consisting of up to three clinical sites responsible for subject recruitment and specimen collection, an analytical core for genomic and proteomic analyses, and a data management, statistics, and informatics core for data management, according to the RFA.

The network will conduct studies using genomic and proteomic approaches and will make the results available in a public database. The goal is to understand the mechanisms responsible for premature birth.

Applications for the grant are due Aug. 20. The RFA can be found here.

EMD to Provide Reagents to TAP

Madison, Wis.-based EMD Biosciences announced this week that it will offer protein purification reagents for an automated protein production system made by The Automation Partnership.

According to the terms of the deal, EMD will combine its Novagen-brand cell culture, lysis, and affinity purification reagents with TAP’s Piccolo system for the automated production of recombinant proteins.

Molecular Connections Signs on With Canadian Distributor

Bangalore, India-based Molecular Connections announced this week that it has signed on United Bioinformatica as a Canadian distributor of its Netpro protein interaction database and custom literature curation services.

Netpro contains over 34,000 curated and annotated protein interactions from published biomedical literature, as well as protein-DNA and protein-small molecule interactions, Molecular Connections said.

United Bioinformatica, based in Calgary, Canada, provides software for laboratory information management systems, microarray expression analysis, proteomics, data mining, and sequence analysis.

Tienta Makes First Sale

Indianapolis, Ind.-based Inproteo spin-off Tienta Sciences announced this week that it has made the first sale of its SpectRIM product, to tool-maker Jobin Yvon-Horiba. Jobin Yvon manufactures analytical Raman, reflectance IR spectroscopy, and mass spectrometry. SpectRIM is a substrate that allows for Raman and Infrared spectroscopy, as well as MALDI mass spec analysis, on a single protein sample (see PM 4-23-04).

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.