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News Briefs: Ultraflex, AP-MALDI and 1100 series LC/MSD Trap, ProteinChip



BDAL’s Q1 New Bookings Rise by 25 Percent

Bruker Daltonics said last week that its new order bookings for life-science systems grew by 25 percent during the first quarter of 2002, compared with the same quarter of 2001. “We see real excitement and increasing demand for our Ultraflex TOF/TOF system,” Frank Laukien, Bruker Daltonics’ CEO, said in a statement. “Our shipments and installations for the Ultraflex are ramping up smoothly.”


Agilent to Use MassTech’s AP-MALDI in New Mass Spec

Agilent Technologies and Burtonsville, Md.-based MassTech agreed last week to customize a version of MassTech’s atmospheric pressure MALDI (AP-MALDI) ion source for use with the Agilent 1100 series LC/MSD Trap ion trap mass spectrometer, and possible future mass spectrometers. The new instrument will have MS/MS capabilities, and can detect absolute sample amounts in the low femtomole range spotted onto the sample plate, Agilent said. The company has not released a price for the mass spectrometer, but said in a statement that it would offer tandem mass spectrometry capabilities at a fraction of the cost of a Q-TOF or MALDI-TOF mass spectrometer. Agilent expects to begin shipping the instrument in late summer 2002.


Harvard Researchers Identify Biomarker With Ciphergen Platform

In a presentation at the annual meeting of the American Association of Cancer Research April 8, researchers from the Brigham & Women’s Hospital of Harvard Medical School reported that they had identified a potential biomarker for ovarian cancer using Ciphergen’s SELDI ProteinChip system, Ciphergen said in a statement. The researchers, led by Samuel Mok, found that an 11.7 kDa protein, the alpha chain of haptoglobin, was elevated in a majority of serum samples taken from ovarian cancer patients. In a screen of 171 samples, Mok and his colleagues determined that the presence of the haptoglobin peak gave 90 percent specificity and 71 percent sensitivity, an accuracy greater than any currently available blood test for ovarian cancer, according to Ciphergen.

The Scan

Gone, But Now Reconstructed SARS-CoV-2 Genomes

In a preprint, a researcher describes his recovery of viral sequences that had been removed from a common database.

Rare Heart Inflammation Warning

The Food and Drug Administration is adding a warning about links between a rare inflammatory heart condition and two SARS-CoV-2 vaccines, Reuters reports.

Sandwich Sampling

The New York Times sent tuna sandwiches for PCR analysis.

Nature Papers Describe Gut Viruses, New Format for Storing Quantitative Genomic Data, More

In Nature this week: catalog of DNA viruses of the human gut microbiome, new dense depth data dump format to store quantitative genomic data, and more.