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New Proteomics Products From Pittcon

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LC Packings/Dionex introduced a new Dual Gradient UltiMate Capillary/Nano LC system that allows for parallel capillary/nano LC separations. The system consists of two micropumps, capable of gradient flow rates as low as 50 nl/min.

Beckman Coulter launched its A2 Protein MicroArray platform. It allows for the analysis of up to 13 different analytes in each well of a 96-well plate. The system comprises 96-well plates pre-spotted with oligos, a universal linker reagent kit that sells for $430, a plate reader for $74,000, and software.

Waters released Alliance MD, a new HPLC system for the analysis of complex protein mixtures. It promises enhanced robustness for operation under harsh salt and pH conditions and can be interfaced with Waters and Micromass TOF and quadrupole mass spectrometers.

Thermo Electron introduced a new 100 µm Kappa capillary column for use with electrospray mass spectrometry. The columns are available from 50 mm to 250 mm with a range of packing materials.

The Scan

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.

Study Tracks Outcomes in Children Born to Zika Virus-Infected Mothers

By following pregnancy outcomes for women with RT-PCR-confirmed Zika virus infections, researchers saw in Lancet Regional Health congenital abnormalities in roughly one-third of live-born children.

Team Presents Benchmark Study of RNA Classification Tools

With more than 135 transcriptomic datasets, researchers tested two dozen coding and non-coding RNA classification tools, establishing a set of potentially misclassified transcripts, as they report in Nucleic Acids Research.

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.