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New Products: Roche

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Roche this week launched its Complete His-Tag purification column for purifying histidine-tagged proteins from cell lysates.

The column uses Roche's nickel-chelate chemistry and is compatible with commonly used reducing agents, metalloproteinase inhibiting reagents, and different buffer and salt environments allowing researchers to choose optimal conditions, the company said. Additionally, the columns require no buffer exchange or resin recharging following purification.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.