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New Products with Proteomic Applications from Pittcon 2006
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Company
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Product Name
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Description and Applications
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| Agilent | 1200 Single Quad mass spectrometer |
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Instrument has doubled throughput of Agilent's previous single quad. For more details, see ProteoMonitor 2/2/2006. |
| Agilent | 6210 TOF mass spectrometer |
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Instrument offers over four times the throughput of Agilent's previous TOF, better than 3 ppm mass accuracy, and three to four orders of magnitude in spectrum dynamic range. Scans five to 10 times per second over a wide mass range. For more details, see ProteoMonitor 2/2/2006. |
| Agilent | 6300 Series Ion Trap mass spectrometer |
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Ion trap's Electron Transfer Dissociation fragmentation technique offers new capabilities in post-translational modification analysis. For more details, see ProteoMonitor 2/2/2006. |
| Agilent | 6410 Triple Quadrupole LC/MS |
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At a cost of $205,000, the instrument is priced "30 to 50 percent lower than comparable instruments," according to Agilent. For more details, see ProteoMonitor 2/2/2006. |
| Agilent | 6510 Q-TOF mass spectrometer |
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Instrument offers attomole sensitivity for MS and MS/MS, and a mass accuracy of 1 ppm to 3 ppm for MS, and 5 ppm for MS/MS. Scans at speed of 20 scans per second, and has up to 15,000 resolving power. For more details, see ProteoMonitor 2/2/2006. |
| Agilent | MassHunter Bioconfirmation software |
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Designed to confirm identities of known proteins or peptides by generating accurate lists of peptide mass, retention time, and abundance. |
| Agilent | MassHunter Profiling software |
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Designed to reveal relevant differences between samples — for example, differences in expression of peptides, proteins, or metabolites. |
| Agilent | MassHunter Workstation software |
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Software supports Agilent's new 6000 series mass specs. Applications include instrument control, data acquisition, and qualitative and quantitative analysis. Software currently does not support Agilent's older mass specs. |
| Agilent | Spectrum Mill for MassHunter Workstation |
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New version supports a wide variety of stable isotope-based labeling strategies. |
| Applied Biosystems | QSTAR Elite Q-TOF mass spectrometer |
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Launched in January, this instrument has a sub-3 ppm mass accuracy and a scan speed of 20 spectra per second in full-scan MS mode, and seven MS/MS spectra per second in automated information-dependent acquisition mode. Its sensitivity, resolution, mass accuracy, linear dynamic range, and speed are better than ABI's previous QSTAR XL system. |
| Bruker Daltonics | Apollo II Dual Source |
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Allows for simultaneous integration of MALDI and electrospray ionization sources into Bruker's apex line of hybrid Q-q-FTMS mass specs. |
| Bruker Daltonics | MALDI BioTyper |
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Uses protein "fingerprints" measured by MALDI-TOF mass spectrometry to identify and classify microorganisms. |
| Bruker Daltonics | MALDI Molecular Imager |
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Combines MALDI-TOF mass spec technology with histological tissue imaging. Particularly suited to monitoring the spatial distribution of biomarkers in tissue sections. Uses Bruker's proprietary smartbeam laser technology. |
| Bruker Daltonics | PTMscan |
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Applies electron transfer dissociation to Bruker's HCTultra high-capacity ion trap mass spec. Particularly useful for analyzing post-translational modifications. |
| Bruker Daltonics | R-series of refrigerated magnets |
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Refrigerated magnets for Bruker's apex line of hybrid Q-q-FTMS mass specs. Magnets are lower maintenance and smaller than their conventional counterparts. |
| Cerno Bioscience | MassWorks software |
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Software package uses company's patented MSIntegrity technology to achieve higher mass accuracy. Software can improve mass accuracy of unit mass resolution mass specs by up to 100 times, to 5 ppm, according to Cerno. For high-resolution mass specs, software can improve mass accuracy by about three times. |
| Dionex | UltiMate 3000 series of HPLC systems |
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Features dual pump, autosampler, and large dynamic flow rate. Available with monolithic columns. System is controllable by a number of mass spec softwares, including Thermo's Xcalibur, ABI's Analyst, and Bruker's HyStar. |
| Shimadzu | Prominence High-Throughput HPLC |
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Uses 2.2 micron packing material columns which, according to Shimadzu, generate less than half the backpressure compared with other commercially available sub-2 micron columns. |
| Thermo Electron | Finnigan LXQ linear ion trap mass spectrometer |
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Introduced towards the end of 2005, this linear ion trap has a simpler design than Thermo's LTQ-FT and LTQ-Orbitrap that results in a slighly lower sensitivity and significantly lower cost. |
| Thermo Electron | Pulsed-Q Dissociation fragmentation technique |
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Introduced towards the end of 2005, this new fragmentation technique eliminates the low mass cut-off for ion traps and enables quantitation with iTRAQ labling reagents. |
| Varian | 15T Fourier Transform Mass Spectrometry system |
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World's first 15 Tesla FTMS. Equipped with the strongest magnetic field magnet commercially available, this FTMS is particularly suited for analysis of large biomolecules, such as in top-down proteomics, and for the analysis of complex samples, such as serum and plasma, that have large dynamic ranges. Time from order to delivery is approximately one year. |
| Waters | Acquity UPLC Column Manager |
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New column switcher can handle higher temperatures — a feature that could be important in speeding up separations during proteomics experiments. |
| Waters | Protein Lynx Global Server software, version 2.2.5 |
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New version supports isotopic labeling technologies as well as label-free quantification. See ProteoMonitor 2/16/2006) for more details. |
| Waters | UPLC Amino Acid Analysis Application Solution |
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System for UPLC analysis of amino acids includes UV-based Acquity UPLC system and an AccQ Tag Ultra Chemistry Kit consisting of a quality-controlled amino acid analysis column, eluents, derivitization reagents and standards. |
| Waters | UPLC Peptide Mapping Application Solution |
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System offers significantly better resolution and sensitvity than traditional LC when applied to protein identification, according to Waters. Includes UV-based Acquity UPLC system, the BEH130 and BEH300 peptide mapping columns, and a system PQ kit that includes a column and two peptide standards. |
| Wyatt Technology | DynaPro Titan Plate Reader |
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Automated Dynamic Light Scattering system for characterizing protein homogeneity within a solution operates with as few as 50 microliters of sample per well. |
New Products with Proteomic Applications from Pittcon 2006
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