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New Products With Proteomic Applications Introduced at ASMS 2005

New Products With Proteomic Applications
Introduced at ASMS 2005
Product Name
Description and Applications
Agilent Technologies Electron
Transfer Dissociation
Designed to be used with the XCT Ultra ion-trap mass spec to enhance results for reserachers doing de novo sequencing and post-translational modification analysis.
Agilent Technologies Proteomics Software: BioConfirm, Mass Profiler, Spectrum Mill, GlycomIQ
BioConfirm is designed to deconvolute intact protein and peptide mass spectral data; Mass Profiler processes Agilent TOF MS data using a unique Mass Hunter algorithm; Updated Spectrum Mill has iterative database searching and content-based scoring for protein identification confidence and relative quantification; GlycomIQ is designed for analysis of glycoproteins.
Alfa Wasserman Continuous Flow Ultracentrifuge
Ultracentrifuge for high-resolution separation and concentration of subcellular organelles. Can handle 1.5 to 2 L of fluid.
Applied Biosystems/ MDS Sciex MarkerView Software
Software package is designed for metabolomics and biomarker-profiling analysis.
Bruker Daltonics Clinprot beads
Three new types of beads: Large-Protein Beads that can be used for proteins with molecular weights of 10-100 kilodaltons, and beyond; Glyco-Beads for enrichment of glycoproteins; and Antibody-Capture beads for specific enrichment of different protein groups with the same antigen specificity.
Bruker Daltonics Electron Transfer Dissociation Fragmentation module
Designed to be used with the HCTultra ion-trap mass spec, the module preserves post-translational modifications, such as phosphorylation or glycosylation.
Bruker Daltonics Proteineer-LC 1.1
Upgraded software enables quantification analysis. Compatible with ICPL.
Bruker Daltonics/Serva Electrophoresis GmbH Isotope Coded Protein Label
New protein-quantification labeling technology tags lysine side chains.
GE Healthcare DeCyder MS
Differential protein expression analysis software takes LC-MS data and creates two- or three-dimensional intensity maps. Allows relative quantitation without the need for mass-tag chemistry, company says.
Invitrogen/ Applied Biosystems SILAC
Protein identification and quantification labeling technology. Tags tryptic peptides via incorporation of special amino acids during cell growth.
Proteome Software Scaffold
Proteomics software tool allows for extracting more detailed and accurate information from Sequest or Mascot results
Thermo Electron H-ESI probe with Dual Desolvation Zone Technology
Heated electrospray ionization probe is designed to work with the Finnigan TSQ Quantum Ultra triple quadrupole mass spectrometers. Probe increases sensitivity and selectivity.
Thermo Electron LTQ Orbitrap mass spectrometer
New type of hybrid mass spectrometer designed for small molecules. Uses novel type of mass analyzer.
Thermo Electron Watson LIMS-Xcalibur Digital Interface
Bi-directional digital interface between Watson LIMS and Xcalibur mass spectrometry software.
Waters Enhancements to nanoACQUITY Ultra Performance LC System
Enhancements include an increase in operating pressure from 5000 psi to 10,000 psi, a new fraction collector for LC/MALDI analysis, and off-line two-dimensional LC applications.
Waters MassLynx 4.1 TOF enhancements
Enhancements to software improve control of LCT Premier and Q-Tof Premier mass spectrometers, resulting in improved characterization of phosophopeptides and glycopeptides.
Waters MassPREP Phosphopeptide Standards
Kits optimize analysis and detection of phosphopeptides during liquid chromatography and mass spec analysis.
The Scan

Long COVID-19 Susceptibility Clues Contained in Blood Plasma Proteome

A longitudinal study in eBioMedicine found weeks-long blood plasma proteome shifts after SARS-CoV-2 infection, along with proteomic signatures that appeared to coincide with long Covid risk.

Tibetan Study Finds Adaptive Variant Influencing Skin Pigmentation

With a combination of phenotyping and genetic data, researchers document at PNAS a Tibetan-enriched enhancer variant influencing melanin synthesis and ultraviolet light response.

Domestication Linked to Nervous System Genes in Inbred Mouse Strains

Researchers highlighted more than 300 positively selected genes in domesticated mice, including genes linked to nervous system function or behavior in Genome Biology.

ALS Genetic Testing May Be Informative Across Age Ranges, Study Finds

Researchers in the journal Brain identified clinically actionable variants in a significant subset of older ALS patients, prompting them to point to the potential benefits of broader test use.