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New Products: Agilent, Thermo Fisher Scientific

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Agilent this week introduced its AdvanceBio Peptide Mapping BioHPLC and ZORBAX RRHD 300-HILIC columns for the analysis of proteins, monoclonal antibodies, peptides and additional biologics.

According to the company, the columns allow for peptide mapping at two to three times the speed of conventional fully porous HPLC columns.


Thermo Fisher Scientific said this week that a number of its chromatography systems are now compatible with Waters' Empower Chromatography Data Software.

The compatible equipment includes the company's Dionex ICS-900, ICS-1100, and ICS-1600 systems as well as the Dionex ERC 10 Eluent Regeneration Controller, the Dionex UltiMate 3000 rapid separation thermostatted open autosampler, the UltiMate 3000 quaternary rapid separation pump with extended pressure range, and the Dionex Corona ultra RS charged aerosol detector.

The Scan

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.

Study Explores Animated Digital Message Approach to Communicate Genetic Test Results to Family Members

In the Journal of Genetic Counseling, the approach showed promise in participants presented with a hypothetical scenario related to a familial hereditary breast and ovarian cancer syndrome diagnosis.

Computational Tool Predicts Mammalian Messenger RNA Degradation Rates

A tool called Saluki, trained with mouse and human messenger RNA data, appears to improve mRNA half-life predictions by taking RNA and genetic features into account, a Genome Biology paper reports.

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.