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New Products : Mar 12, 2009


At Pittcon this week, Waters launched the Empower 2 Business Intelligence Manager software for the analysis of chromatography analysis.

The software captures data such as the number of samples run by a chromatographic system, number of injections or methods utilized by project of chromatographic system, and chromatographic-system use by personnel and "aggregates this raw utilization data from all systems on the Empower 2 network and converts that data into easy-to-read dashboard visualizations that ultimately provide lab managers with an added analytical dimension: analysis of their LC operations," Thomas Tucker, informatics product manager for Waters, said in a statement.

The company also introduced DriftScope 2.0 Mobility Environment Software, which extends the discovery power and accessibility of Waters' Synapt HDMS. The software automates "many aspects" of data analysis that once required expert skills, the company said, and provides more efficient links to downstream interpretative data software.

In addition, the company introduced the Local Console Controller, a PDA-like device for monitoring the status of the firm's Acquity UPLC systems. And it announced the expansion of its LC system qualification tool for its Empower Chomatography software, which now supports Agilent's 1100 and 1200 series HPLC instruments.

Also, Agilent Technologies launched the 1200 Series HPLC-Chip II, the second generation of its nano liquid chromotagraphy/electrospray system for mass spectrometry.

The new platform is designed to give two times the life of the original HPLC-Chip.

Agilent incorporated proprietary ion implementation technology to the new chips, extending the life of them to more than 1,000 injections. A phosphopeptide chip for post-translational modifications will be the first one incorporating the new design. In coming months, the technology will be extended across the entire HPLC-Chip family, the company said.

UK sensor firm Stratophase launched its SpectroSens technology for the real-time determination of reaction kinetics.

The technology is based on "principles which measure changes in the refractive index of liquids," the company said in a statement. In native form, the sensors monitor the relative compositions of liquids, and when functionalized they can detect biological targets, such as proteins, viruses, and bacteria.

The core of the technology is an optical silicon chip, which by measuring the refractive index analyzes changes on any liquid on the surface of the chip. It also directly measures the binding of antigens to antibodies attached to the chip surface. "The result is a small, versatile and accurate device, which can be used for laboratory analysis or in the field for chemical monitoring and bio-detection," Stratophase said.

Outside of Pittcon, BiOptix launched its 207B multiplex label-free molecular interaction instrument.

According to the company, the platform has 10 times the sensitivity of competing instrument; offers on-chip control for background effects such as non-specific binding; and use-customizable biochips that are chemically modified outside the instrument and are easily manipulated.

The technology is expandable up to 96 features per array.

Proxeon said this week that its ProteinCenter data interpretation tool now allows researchers to link identified proteins directly to the biological pathways in which they are involved.

ProteinCenter is a consolidated, biologically annotated protein sequence database derived from all major protein databases. It allows for filtering, clustering, and statistical bioinformatics analysis from a single, combined, or comparison datasets, Proxeon said in a statement.

The Plant Proteome Database has been expanded to include the whole plant proteome, Cornell University said last week.

The bioinformatics infrastructure for the database was generated using the resources of the Cornell Center for Advanced Computing.

"Most cellular functions are carried out by proteins, therefore knowing the complete set of expressed proteins, their subcellular localization and interactions is essential," said Klaas van Wijk, an associate professor of plant biology at Cornell, in a statement. He and Qi Sun of the Cornell Computational Biology Service Unit initiated the PPDB.

More than 5,000 accessions in both maize and Arabidopsis have been identified, the university said. Also more than 80 published Arabidopsis proteome datasets from subcellular compartments of organs are stored in the PPDB and linked to each locus. More than 1,500 Arabidopsis proteins have a manually assigned subcelluar location, with a strong emphasis on plastid proteins.

New features of the PPDB include searchable post-translational modifications and searchable experimental proteotypic peptides and spectral count information for each identified accession based on in-house experiments.

Search methods are also provided for the extraction of more than 40 data types for each accession and for the extraction of accessions for different functional categories or curated subcellular locations.

The database is continually updated with in-house experimental datasets as well as external datasets, and the university is working with other research community databases such as the Arabidopsis Information Resource and Gramene to distribute the PPDB data, Cornell said.

PPDB content can be accessed through its Web interface.

The Scan

Boosters Chasing Variants

The New York Times reports that an FDA advisory panel is to weigh updated booster vaccines for COVID-19.

Not Yet

The World Health Organization says monkeypox is not yet a global emergency, the Washington Post reports.

More Proposed for Federal Research

Science reports that US House of Representatives panels are seeking to increase federal research funding.

PLOS Papers on Breast Cancer Metastasis, Left-Sided Cardiac Defects, SARS-CoV-2 Monitoring

In PLOS this week: link between breast cancer metastasis and CLIC4, sequencing analysis of left-sided cardiac defects, and more.