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New Products: Feb 11, 2011

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Thermo Fisher Scientific this week released its new Pierce GTPase Enrichment Kit for profiling GTPases and G-protein subunits in tissues, cells, and subcellular proteomes.

The kit uses desthiobiotin-nucleotide probes that enable easy reversal of the capture bond by biotin displacement, low pH, or heat, allowing for study of the isolated proteins via Western blot or mass spec, the company said.


Pressure BioSciences this week introduced four new products it plans to release between 2011 and 2013.

The products are the Barocycler HUB440 – a high pressure generator for a variety of sample prep applications to be released in Q3 2011; the Barocycler FFPE Protein Extraction Service – a service using pressure cycling for the extraction of proteins from formalin-fixed, paraffin-embedded samples to be launched in 2012; the XstreamPCT HPLC Digestion Module – a PCT-enhanced protein digestion system and the first module in the company's pressure cycling based HPLC system; and the Barocycler HT Multiwell – a device for pressure cycling enhanced biomolecule extraction and enzymatic digestion.

The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.