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New Products: Dec 10, 2010


GE Healthcare has extended its line of HiScreen prepacked chromatography columns, bringing the total number of media available in that format to 23.

The four new offerings are: Ni Sepharose 6 Fast Flow columns for applications like purification of histidine-tagged recombinant proteins; Blue Sepharose 6 Fast Flow columns for binding proteins like albumin, interferon, and blood coagulation factors as well as kinases, dehydrogenases, and most enzymes requiring adenyl-containing cofactors; DEAE Sepharose Fast Flow columns for medium and weak anion exchange; and Butyl Sepharose High Performance columns for hydrophobic interaction chromatography.

Protein Discovery has released two new sample-preparation kits for mass spectrometry-based proteome research — the FASP Protein Digestion Kit and the FFPE-FASP Protein Digestion Kit.

The FASP kit enables the use of strong detergents in mass spec workflows, offering standardized sample prep for both soluble and insoluble proteins in fluids and tissues, the company said. The FFPE-FASP kit is designed to allow compatibility of formalin-fixed paraffin-embedded samples with downstream mass spec sample-prep techniques.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.