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New Products: May 28, 2010

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A number of vendors introduced new proteomics products at the American Society for Mass Spectrometry meeting in Salt Lake City this week. The following is a roundup of new offerings introduced at the conference.


Thermo Fisher debuted its new ISQ single quadrupole GC-MS as well as new Pierce Detergent Removal Spin Columns and Pierce Graphite Spin Columns for protein sample preparation.

The ISQ uses the ExtractaBrite ion source, which allows for easy removal of the system's ion source for maintenance, increasing uptime and productivity, the company said in a statement.

The Pierce Graphite Spin Columns enable improved purification of phosphopeptides, allowing for better mass spec analysis of samples from protein digests, strong-cation ion exchange fractions and enriched phosphopeptides eluted from TiO2 and immobilized metal affinity chromatography columns and tips, the company said. The Pierce Detergent Removal Spin Columns aid in the removal of detergents like SDS from protein and peptide samples to prepare them for downstream analysis.


Bruker introduced this week its new MALDI-solariX — a solariX FTMS-based MALDI system — and its amaZon SL — a new entry-level ion trap mass spectrometer.

The MALDI-solariX combines the high analytical power of the solariX FTMS platform with a MALDI source to offer high-performance molecular imaging of small molecules, the company said in a statement. It also features a dual ion funnel design that allows switching between MALDI and ESI.

The amaZon SL also features the dual ion funnel technology and offers scan speeds of up to 32,000 u/s at full isotopic resolution.


Waters introduced at the conference its new Xevo TQ-S tandem mass spectrometer.

The instrument accurately measures target compounds in complex samples at femtogram levels and can obtain full scan MS and MRM data simultaneously on narrow 1-2 second wide UPLC peaks while still obtaining greater than 12 points across the peak, the company said in a statement.


Shimadzu Scientific Instruments launched its new AXIMA MegaTOF — a high-sensitivity MALDI device developed in partnership with CovalX.

The instrument combines Shimadzu's linear MALDI TOF mass spectrometer with a CovalX high-mass detection system, which allows for detection of macromolecules of up to 1,500 kDa and the analysis of intact protein complexes, the company said in a statement.


Agilent Technologies introduced its mAb-Glyco-Chip — a new HPLC-Chip designed to aid in N-glycan analysis.

HPLC-Chip technology allows for N-glycan analysis in a matter of tens of minutes, the company said in a statement, compared to two to three days with conventional methods like LC-FLD or CE-FLD. Agilent now offers 13 different versions of HPLC-Chips for applications including peptide quantitation, targeted phosphopeptide analysis, and small molecule DMPK studies.


Bio-Rad Laboratories announced this week the launch of its Redfin 2D gel analysis service.

The Redfin service uses a downloadable software interface to let researchers upload their 2D gel images for analysis by a team of Redfin gel analyzers. Image analysis consists of spot detection and segmentation, spot matching, and quantification and normalization.

The service is available through a partnership between Bio-Rad and bioinformatics firm Ludesi, which developed the Redfin technology.

The Scan

Review of Approval Process

Stat News reports the Department for Health and Human Services' Office of the Inspector General is to investigate FDA's approval of Biogen's Alzheimer's disease drug.

Not Quite Right

A new analysis has found hundreds of studies with incorrect nucleotide sequences reported in their methods, according to Nature News.

CRISPR and mRNA Together

Time magazine reports on the use of mRNA to deliver CRISPR machinery.

Nature Papers Present Smartphone Platform for DNA Diagnosis of Malaria, Mouse Lines for Epigenomic Editing

In Nature this week: a low-cost tool to detect infectious diseases like malaria, and more.