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New Products: May 14, 2010

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Olink Bioscience this week launched the Duolink II reagent kit, Duolink ImageTool, and Duolink II Probemaker.

The reagent kit has a new formula, and in combination with fewer steps and a "significantly" shorter protocol, is more user-friendly and efficient, the Swedish company said in a statement.

The Duolink ImageTool is imaging software for the analysis of cells and tissue sections processed with the Duolink reagents. Each signal generated from the reagent can be individually quantified by the software, "enabling single cell statistical analysis of expression levels in tissue or cell populations," the company said.

The Duolink Probemaker kit enables "quick and convenient" conjugation of Olink's PLA oligonucleotide arms directly to primary antibodies, eliminating the need for PLA probes based on secondary antibodies, the company added. As a result, it is possible to use same-species monoclonal or polyclonal antibodies in a Duolink assay and opens up the possibility of studying homodimeric protein complexes, Olink said.


AnaSpec this week launched its ClearPoint beta-amyloid custom peptide synthesis service.

ClearPoint peptides are AnaSpec's collection of heavy or stable isotope-labeled peptides and amino acids. The peptides can be used for the quantitative analyses of beta-amyloid peptides in fluids by mass spectrometry, and the inclusion of internal heavy isotope-labeled peptide standards makes mass spectrometry a method for absolute quantitation for the peptide of interest, according to AnaSpec.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.