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New Products: Mar 26, 2010

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Eksigent introduced the ExpressLC-Ultra at Pittcon held earlier this month.

The microscale HPLC runs at column pressures up to 10,000 psi, allowing the use of sub-2 micron particle columns. The instrument has a new UV detection system, and delivers the advantages of microscale LC, such as solvent savings, reduced sample requirements, and reduced frictional heating, Eksigent said in a statement.

The system's CCD-based UV detector works with microfabricated flow cells "to ensure ultra-high sensitivity with no band broadening," Eksigent said. Its high sensitivity enables the detection of impurities at levels as low as 0.05 percent, the company added.


Protein Discovery this week launched a line of cartridge kits for its Gelfree 8100 fractionation system.

The kits allow researchers to perform molecular-weight fractionation with liquid phase recovery over various target mass ranges, the company said in a statement.

The Low Mass Cartridge Kit provides “maximum” separation resolution of proteins with molecular weight below 60 kDa. The Mid Mass Cartridge Kit is for separation of proteins between 3.5kDa and 150 kDa in mass, and the High Mass Cartridge Kit is designed for targeted enrichment of intact biotherapeutics, providing resolution in the mass range of 60 kDa and 300 kDa.


ChromoTek this week launched the RFP-Trap to identify and pull down interaction partners of proteins tagged with red fluorescent protein, and the GFP Booster, to increase the green fluorescent protein signal in super-resolution microscopy.

According to the German firm, RFP-Trap is used for biochemical and cell biological analysis of RFG-tagged fusion proteins in pull-down assays, a frequently used in vitro method for determining physical interaction between two or more proteins.

GFP Booster consists of a chemical fluorescent dye covalently attached to a GFP nanotrap, which provides high fluorescence intensities and signal-to-noise ratios, the company said.

The Scan

Push Toward Approval

The Wall Street Journal reports the US Food and Drug Administration is under pressure to grant full approval to SARS-CoV-2 vaccines.

Deer Exposure

About 40 percent of deer in a handful of US states carry antibodies to SARS-CoV-2, according to Nature News.

Millions But Not Enough

NPR reports the US is set to send 110 million SARS-CoV-2 vaccine doses abroad, but that billions are needed.

PNAS Papers on CRISPR-Edited Cancer Models, Multiple Sclerosis Neuroinflammation, Parasitic Wasps

In PNAS this week: gene-editing approach for developing cancer models, role of extracellular proteins in multiple sclerosis, and more.