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New Products: Mar 19, 2010


GE Healthcare this week launched the Sensor Chip CM7 for use on the company's Biacore systems.

The chip has the high immobilization capacity required to support fragment-based screening of small molecules, the company said in a statement. In addition to high signal-to-noise ratios resulting in improved screening data quality, the chip provides improved detection in cases where immobilization levels are unfavorable, including low target protein concentration levels, or proteins that are sensitive to optimal immobilization conditions.

The Sensor Chip CM7 has a carboxymethylated dextran matrix covalently attached to gold film. It is capable of binding proteins, nucleic acids, carbohydrates, or small molecules to carboxyl groups on the sensor surface.

Agilent Technologies said this week that its 1290 Infinity LC is equipped with the 1290 Infinity Diode Array Detector, a new optical design based on the company's Max-Light flow cell with optofluidic waveguides.

As a result, the system has higher levels of UV detection sensitivity and baseline robustness. A path length of 60 millimeters achieves sensitivity 10 times greater than the current industry-leading 1200 Series DAD, the company said in a statement.

The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.