GE Healthcare this week launched the Sensor Chip CM7 for use on the company's Biacore systems.
The chip has the high immobilization capacity required to support fragment-based screening of small molecules, the company said in a statement. In addition to high signal-to-noise ratios resulting in improved screening data quality, the chip provides improved detection in cases where immobilization levels are unfavorable, including low target protein concentration levels, or proteins that are sensitive to optimal immobilization conditions.
The Sensor Chip CM7 has a carboxymethylated dextran matrix covalently attached to gold film. It is capable of binding proteins, nucleic acids, carbohydrates, or small molecules to carboxyl groups on the sensor surface.
Agilent Technologies said this week that its 1290 Infinity LC is equipped with the 1290 Infinity Diode Array Detector, a new optical design based on the company's Max-Light flow cell with optofluidic waveguides.
As a result, the system has higher levels of UV detection sensitivity and baseline robustness. A path length of 60 millimeters achieves sensitivity 10 times greater than the current industry-leading 1200 Series DAD, the company said in a statement.