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New Products: Feb 5, 2010

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NanoInk's Nano BioDiscovery division launched its Human Inflammation Cytokine Assay, the company's first completely configured protein array kit.

The fluorescence assays are based on NanoInk's Dip Pen Nanolithography platform and enable nanoscale detection of clinically relevant proteins, the company said in a statement. The assays measure a panel of 10 cytokines: IL-1alpha; IL-1beta; IL-2; IL-3; IL-4; IL-5;IL-6; IL-8; IFNgamma; and TNFalpha, and a positive and negative control.

The kit includes nanoarrays of analyte-specific antibodies and controls deposited on 1-inch by 3-inch modified glass slides. Each slide is composed of 18 sub-arrays with 48 features per array.

Assays targeting proteins implicated in other various disease states and toxicological responses are being developed for launch this year, NanoInk said.



Thermo Fisher Scientific
this week introduced its Thermo Scientific Aspire Protein A, Protein G, and IMAC Cobalt Chromatography Tips.

The proteomic tips are 1 ml pipette tips embedded with Thermo Scientific Pierce resins. Up to eight samples can be processed in parallel within 20 minutes without the need for centrifugation with the tips, the company said in a statement.

The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.