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New Products: Jul 16, 2009

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LifeSensors last week launched its Chop2 Reporter Assay Kits for deubiquitylases and announced the "imminent launch" of its ubiquitin ligase assay kits.

The technologies are licensed from Progenra which developed them.

In a statement, LifeSensors said that the conjugation and deconjugation of ubiquitin and ubiquitin-like proteins are of "intense" interest to academia and pharma "due to their central roles in human health and disease," and research in such pathways are likely to lead to "many pioneering drugs."

Benefits of the Chop2 Reporter Assay Kits include sensitive, rapid, and robust fluorescent readouts of enzymatic activity within a half-hour with "minimal interference from screening compounds," the company said.

Malvern, Penn.-based LifeSensors specializes in protein expression technologies, ubiquitin pathway research tools, and protein microarrays.


AnaSpec last week launched the Z-Fish series of antibodies, raised strictly from peptide antigens derived from zebrafish protein sequences.

The antigens used in raising the antibodies include non-phosphorylated and phosphorylated peptides. The antibodies are available in 150 microliter size, which is optimal for 15 mini gels, AnaSpec said.

The antibodies being released are for MMP-2, 9, 11, 13, 14, 17, and 24 and were raised from sequences derived from the hinge region, internal, or C-terminal sequence. Other Z-Fish antibodies that will be released soon are for MMP-18 (IN), MMP-18 (hinge), MMP-21 (IN), and MMP-28 (hinge).

The Scan

Cell Atlas of Human Lung Development Gives View of Developing Airway

Researchers have generated a cell atlas of human lung development, which they report in Cell.

Study Finds Costs of Genome Sequencing May Limit Utility in Routine Care

Researchers report in the European Journal of Human Genetics that genome sequencing for rare disease diagnoses currently has similar benefits as less expensive exome analysis.

Study Suggests Nursing Mother's Diet Can Impact Offspring's Gut Microbiome

A new Cell Host and Microbe paper finds that mice whose mothers were fed a low-fiber diet during nursing experience lasting microbiota dysbiosis and increased obesity.

Study Links Genetic Risk for ADHD With Alzheimer's Disease

A higher polygenic risk score for attention-deficit/hyperactivity disorder is also linked to cognitive decline and Alzheimer's disease, a new study in Molecular Psychiatry finds.