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New Products: May 14, 2009

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Thermo Fisher Scientific this week launched the LTQ Velos and LTQ Orbitrap Velos mass spectrometers.

The LTQ Velos features a new dual pressure trap design and atmospheric pressure ionization source, "making it the world's fastest and most sensitive ion trap mass spectrometer," Thermo Fisher said in a statement.

The instrument's data quality and sensitivity make it "ideal" for analyzing complex mixtures such as the identification of low-level proteins. Multiple fragmentation techniques available on the instrument enable more confident sequence assignment and post-translation modification identification, while faster scan rates reduce cycle times by up to half, doubling the number of proteins and peptides identified.

The Velo can also be upgraded to the LTQ Orbitrap Velos, which incorporates the company's Orbitrap mass analyzer and has a new Higher-Energy Collisional Dissociation cell and dual pressure trap technology, delivering "ultra-high" resolution and accurate mass data, Thermo Fisher said.

According to the company, the high mass accuracy of the LTQ Orbitrap Velos increases the speed and confidence of protein identification in complex samples by minimizing false positives. "The ultra-high resolution delivers certainty in analytical results by enabling molecular weight determination for intact proteins and in-depth analysis of isobaric species," the firm said.

For proteomics researchers, this means the identification of more proteins with increased sequence coverage and higher confidence, it added.


Bruker this week launched the amaZon ETD mass spec for proteomics, part of the firm's new ion trap amaZon series of mass specs.

In addition, the company introduced the amaZon X for small-molecule analysis and the applied markets.

Among the new designs in the amaZon line is the first commercial launch of a double ion funnel transfer in ion traps, setting a new benchmark for sensitivity, according to Bruker; a scan speed of 52,000 microseconds at better than unit resolution "for fastest UPLC applications and maximum duty cycle in data-dependent tandem-MS and MSn"; ion trap mass resolving power up to 20,000 in full scan mode across the 50 to 30,000 m/z range; the latest EDT/PTR technology to provide "extremely" robust and sensitive peptide and protein fragmentation and high PTM throughput; and the company's Zero Delay Alternation acquisition for high-speed ion polarity switching with compromise of sensitivity or time.


GE Healthcare this week released six new HiScreen prepacked chromatography columns, bringing the total number of media available in the HiScreen format to 19.

The columns provide "a solution for fast, easy separations in a convenient format," GE Healthcare said in a statement. The columns are packed with robust media, enabling repeated use with reproducible results.

The new columns are the IMAC Sepharose 6 Fast Flow; Q Shepharose Fast Flow; Sepharose Fast Flow; Q Sepharose High Performance; SP Sepharose High Performance; and the Phenyl Sepharose High Performance.


Lee Biosolutions last week expanded its C-reactive protein line to include recombinant C-reactive proteins.

C-reactive protein is found in blood and serves as a biomarker for inflammation. The St. Louis company now has canine, rat, human, and recombinant C-reactive proteins.

The Scan

Highly Similar

Researchers have uncovered bat viruses that are highly similar to SARS-CoV-2, according to Nature News.

Gain of Oversight

According to the Wall Street Journal, the Biden Administration is considering greater oversight of gain-of-function research.

Lasker for mRNA Vaccine Work

The Scientist reports that researchers whose work enabled the development of mRNA-based vaccines are among this year's Lasker Award winners

PLOS Papers on Causal Variant Mapping, Ancient Salmonella, ALK Fusion Test for NSCLC

In PLOS this week: MsCAVIAR approach to map causal variants, analysis of ancient Salmonella, and more.