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NCI Antibodies Now Available Through DHSB


The National Cancer Institute now has 70 well-characterized monoclonal antibodies against 26 cancer-specific targets in the Developmental Studies Hybridoma Bank at the University of Iowa, the two parties said this week.

The monoclonal antibodies are the first to be deposited in the DSHB and were developed as part of the NCI's Clinical Proteomic Technologies for Cancer program. The NCI began an initiative to create better characterized and better performing antibodies in late 2007 after hearing from researchers about issues surrounding antibody quality [see PM 11/29/07].

Strategic Diagnostics was awarded the first contract by the NCI as part of the antibody project [see PM 04/10/08] while subsequent requests for proposals have been issued. All antibodies developed as a result of the initiative and their antecedent hybridomas are being deposited in the DSHB, which is making them available to researchers at $25 per milliliter.

In an e-mail to ProteoMonitor, Henry Rodriguez, director of the NCI’s Clinical Proteomic Technologies for Cancer program, said "Now that the system is built and functioning, we are encouraging the research community to tell us targets that require affinity capture reagents [to be] developed against. … This information/input will guide us in the selection of future targets."

The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.