NEW YORK (GenomeWeb) – Most plasma metabolites follow a daily rhythm in their expression levels that is muted by sleep deprivation, according to a metabolomic study appearing in the Proceedings of the National Academy of Sciences today.

Researchers led by the University of Surrey's Debra Skene collected plasma samples from a dozen healthy research participants and examined their metabolite levels during a normal sleep-wake cycle and during 24 hours of wakefulness.

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