Researchers at the Max Planck Institute have developed a new method for observing protein-protein interactions by incorporating specially synthesized photo-reactive amino acids into proteins.

The trick to the new method is that two modified, photo-reactive amino acids — photo-leucine and photo-methionine — irreversibly cross-link to other nearby proteins when exposed to ultraviolet light. Researchers can then capture their protein of interest using an antibody, and run a Western blot to see if the protein cross-linked to any other proteins.

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Nov
15
Sponsored by
Twist Bioscience

This webinar will discuss how Amyris, a biotechnology company that develops renewable products for a broad range of applications and industries, uses large-scale microbial engineering to support its manufacturing processes.