Max-Delbruck Team Builds Protein-Array Platform to Study Proteome-Wide PTM Interactions | GenomeWeb

By Adam Bonislawski

Researchers at Berlin's Max-Delbruck Center for Molecular Medicine have developed an array-based platform for the proteome-wide screening of post-translational-modification-dependent protein interactions.

The system uses biotinylated peptides featuring PTMs of interest to probe macroarrays containing up to 7,390 unique proteins, quantifying their interactions via laser-induced fluorescence emission.

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