Mann Lab Develops SILAC-based Approach for Use in Tissue Samples | GenomeWeb

This story originally ran on April 8.

By Tony Fong

Since its development about eight years ago, stable isotope labeling by amino acids, or SILAC, has become a standard method for quantitative proteomics.

But the technique developed in Matthias Mann's laboratory has been largely limited by the fact that it can be used only in cell cultures — not tissue or body fluid samples.

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