Mann Lab Develops SILAC-based Approach for Use in Tissue Samples | GenomeWeb

This story originally ran on April 8.

By Tony Fong

Since its development about eight years ago, stable isotope labeling by amino acids, or SILAC, has become a standard method for quantitative proteomics.

But the technique developed in Matthias Mann's laboratory has been largely limited by the fact that it can be used only in cell cultures — not tissue or body fluid samples.

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The White House has created a list of cuts, including to the NIH, that could be in a budget bill for this year.

The US National Institutes of Health is to allow applicants to cite preprints just as they would any other research paper, ScienceInsider reports.

Two manuscript pages handwritten by Charles Darwin are going on the auction block, according to the Los Angeles Times.

In PNAS this week: tool to track transcriptome-wide binding, evidence of balancing selection on behavior-linked genes, and more.