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Macromolecular Structure Database, Molsoft, Definiens


The Macromolecular Structure Database group at the EBI now offers a platform-independent toolbar application to search the MSD Relational Database. It is available at


Molsoft has released a free program, ICM Browser, that can read PDB files, sequences, alignments, or internal binary multi-object documents, visualize rich sequence-structure, save high-resolution images, create colored alignments, perform PDB searches, annotate structures, and calculate RMSD between structures. It is available at


Definiens has launched version 2.1 of its Proteomweaver 2D gel analysis software. The new version allows users to analyze multiple samples run within the same gel. It uses a new quantification algorithm that has been especially designed for multi-fluorescence gels.


The Scan

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.

Study Reveals Potential Sex-Specific Role for Noncoding RNA in Depression

A long, noncoding RNA called FEDORA appears to be a sex-specific regulator of major depressive disorder, affecting more women, researchers report in Science Advances.

New mRNA Vaccines Offer Hope for Fighting Malaria

A George Washington University-led team has developed mRNA vaccines for malaria that appear to provide protection in mice, as they report in NPJ Vaccines.

Unique Germline Variants Found Among Black Prostate Cancer Patients

Through an exome sequencing study appearing in JCO Precision Oncology, researchers have found unique pathogenic or likely pathogenic variants within a cohort of Black prostate cancer patients.