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John Yates, Lester Crawford, and Mark McClellan

John Yates has been named to the scientific advisory board of Protein Discovery, the company said this week. Yates is a professor of cell biology and the principal investigator of the Proteomic Mass Spectrometry Laboratory at the Scripps Research Institute.

Former US Food and Drug Administration Commissioner Lester Crawford pleaded guilty this week to charges by the US Department of Justice for lying about stock he held while he headed the agency and for conflict of interest.
Each charge carries a maximum penalty of one year in jail.
The DOJ alleged Crawford had said he sold stocks in companies that he and his wife owned that were regulated by the FDA while he was a deputy commissioner at the FDA when, in fact, he had not. Those companies include Sysco, Wal-Mart, and Kimberly-Clark.
Relating to the conflict-of-interest charges, the DOJ said that during a period when he headed the FDA Obesity Working Group,which among other things was looking into calorie content labeling for soft drinks, Crawford held more than $60,000 in shares of Pepsico and $78,000 in shares of Sysco, a food distribution company.
Crawford was also accused of failing to report about $28,000 in income he made from the sale of shares in Embrex while he held a leadership position at the FDA. Embrex is an agricultural biotech company regulated by the FDA.
Crawford headed the FDA for two months before resigning abruptly in September 2005 without stating a reason. He had been the acting head of the agency for more than a year. He is now a senior staff member of Washington DC lobbying firm Policy Directions.


Former FDA Commissioner Mark McClellan, who until Saturday was administrator of the Center for Medicare and Medicaid Services,has joined the AEI-Brookings Joint Center for Regulatory Studies think tankas a visiting senior fellow. He will be working on developing and implementing ideas to improve health care quality.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.