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Invitrogen, Phoenix S&T, Bruker Daltonics, Isis Pharmaceuticals

Invitrogen lauched this week the iBlot Dry Blotting system and the iPrep purification instrument.
The iBlot system transfers proteins from polyacrylamide gels to nitrocellulose membranes in preparation for downstream analysis. The iPrep instrument automates nucleic acid purification using Invitrogen’s ChargeSwitch technology.

Phoenix S&T this week launched its SureSpray technology for mass spectrometry analysis of proteins and metabolites. In a statement, Phoenix said SureSpray’s orifice is larger than that of nanospray ionization technology. That and its inert plastic surfaces reduce the clogging and variation in signal intensity found with the nanospray ionization method, the company said.
The SureSpray is available for shipment and is available in chip format and HPLC columns.

Bruker Daltonics and Isis Pharmaceuticals this week launched the Ibis T5000 biosensor system in Europe. The system is used for the identification and characterization of micro-organisms and uses Bruker’s micrOTOF ESI TOF mass spectrometer.
In July the companies announced an agreement whereby Bruker would be the exclusive worldwide manufacturer of the T5000 system. The agreement gives Bruker exclusive rights to sell T5000 in Europe.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.