Skip to main content
Premium Trial:

Request an Annual Quote

Glycomics Firm Ezose Inks Deal with Merck for Diabetes Biomarker Work

Premium

Glycomics firm Ezose Biosciences said this week it has inked a collaboration agreement with Merck for biomarker discovery research in diabetes.

The research will focus on identifying changes in glycan patterns in human proteins using Ezose’s GlycanMap platform, the firm said, adding that the work follows on previous collaborations between the two companies.

GlycanMap uses an automated 96-well, bead-based glycan enrichment platform linked to MALDI-TOF mass spectrometry to identify and quantify glycans in biological samples like blood and tissue.

Financial and other terms of the agreement were not disclosed.

Ezose also said today it has fully aligned its business with Shionogi's Diagnostics Division following its acquisition by the Japanese drugmaker.

As part of the alignment, Kiyoshi Nagata was named chairman and CEO of Ezose, replacing John Keller, who will continue to serve as a member of Ezose's board, and as president and CEO of Shionogi Inc., the US-based group company of Shionogi. Ezose was formed in 2009 as a US joint venture of Shionogi and Sumitomo Bakelite.

"The alignment of Ezose's biomarker discovery platform with our existing diagnostics and companion diagnostics development and commercialization capabilities provides a unique opportunity for both internal and partnership programs," Nagata said in a statement. "We are bringing the promise of glycomics for biomarkers and personalized medicine into practical use for accelerating drug development and enhancing medical practice."

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.