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GE Healthcare, Genedata

GE Healthcare last week launched the Vivaspin sample concentrator for protein sample preparation.
The Vivaspin product has been sold by German-based firm, Sartorius Stedim Biotech, but is now also being sold by GE Healthcare. Vivaspin provides fast, non-denaturing concentration of up to 30 times from a range of volumes between 100 microliters to 20 milliliters, the company said in a statement.
Sample concentration with Vivaspin is done by membrane filtration in a single tube. The user selects the molecular weight cutoff. The sample is placed in the upper compartment of the tube and centrifugation is applied forcing the solvent through a semi-permeable membrane into the lower compartment of the tube, leaving a more concentrated sample in the upper chamber.

Genedata this week announced the release of its Expressionist 5.0 high-throughput biomarker discovery platform.
Features of the new version of the software include increase accuracy in classification analysis through the use of ROC curves, k-fold cross validation, and other new tools; enhanced “cross-omics” analysis with ExpressMap for analysis of expression data; and improved analysis of ontology relationships through a Gene Ontology browser.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.