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GE Healthcare, Cell Biosciences, Proxeon

GE Healthcare this week launched four new custom-designed BioProcess affinity chromatography media for industrial-scale purifications of various biopharmaceuticals.
They are KappaSelect for antibody fragments for kappa light chain; IgSelect for human IgG; AVB Sepharose High Performance for adeno-associated virus; and VIIISelect for Factor VIII production.
The new media are based on the use of immobilized single-chain antibody fragments as chromatography ligands. BAC, which develops and produces antibody fragments for use in the manufacture of biopharmaceuticals, collaborated with GE in developing the media.
GE’s Custom-Design Media program used the antibody fragments developed by BAC to develop chromatography resins. The program is available to manufacturers to request additional custom media for purification work, GE said in a statement.

Cell Biosciences this week launched the Firefly 3000 Focusing kits, Detection kits, and Plate kits for the Firefly 3000 Protein Analysis System.
The kits are the first assays kits for the system and were designed to provide reproducible analytical results conveniently and flexibly, company said in a statement.
They are available with multiple separation ranges and multiple detection antibodies.

Proxeon this week released ProteinCenter 2.0, an interpretation tool that converts complex proteomics datasets into biological sense in minutes rather than months with conventional solutions.
ProteinCenter 2.0 allows researchers to share datasets with colleagues and collaborators remotely and can “reveal the biological picture concealed within each dataset by enabling comparison of datasets against complete proteomes,” Proxeon said in a statement.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.