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GE Healthcare, Bio-Rad, AnaSpec

GE Healthcare this week introduced launched a protein labeling kit for 2D DIGE.
The kit contains 2 nanomoles each of three CyDye DIGE Fluor minimal dyes Cy2, Cy3, and Cy5, and a free one-month trial license of DeCyder 2D differential analysis software, the dedicated image analysis software for the Ettan DIGE system.
Protein mixtures are labeled prior to electrophoresis with size- and charge-matched, spectrally resolvable CyDye fluors. Following 2D electrophoresis, the results can be scanned with the Typhoon Variable Mode Imager or Ettan DIGE system.

Bio-Rad Laboratories this week launched a new GLH sensor chip for its ProteOn XPR36 protein interaction array system.
The chip is optimized for protein-small molecule interactions as well as protein-protein interactions. It generates a high analyte signal through its high ligand activity and binding capacity and is “expected to deliver an improved surface plasmon resonance signal compared to other commercially available surfaces,” the company said in a statement.

AnaSpec this week introduced two keratin antibodies that recognize the intact and caspase digested N-terminal of K18 and k19 at Asp237.
The antibodies can be used for studying keratin dynamics in mice undergoing hepatocyte apoptosis, patients with cirrhosis, and apoptotic cells of various epithelial human tumors in a non-invasive manner, AnaSpec said in a statement.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.