Skip to main content
Premium Trial:

Request an Annual Quote

Funding Update: NSF Grants Awarded to UW-Madison, University of Michigan


Recent NSF Awards in Proteomics and Protein Research

Title: Amyloid Regulatory Networks
Principal Investigator: Regina Murphy
Sponsor: University of Wisconsin-Madison
Start/End Date: June 1, 2013 – May 31, 2016
Amount Awarded to Date: $390,001

Funds an effort to investigate the non-self association between amyloidogenic proteins, examining roughly 100 different pairs of proteins to determine if they interact. For interacting proteins, experiments will be done to identify the portions of the proteins involved in the interaction and to measure the effect of these interactions on progression on the amyloidogenesis pathway.

Title: Next-Generation Ion Mobility-Mass-Spectrometry of Protein-ligand and Multiprotein Complexes
Principal Investigator: Brandon Ruotolo
Sponsor: University of Michigan Ann Arbor
Start/End Date: May 1, 2013 – April 30, 2018
Amount Awarded to Date: $250,000

Funds development of a mass spec technique combining nanospray ionization with ion-mobility mass spec to investigate drug molecule binding with multi-protein complexes.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.