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Funding Update: NSF Grants Awarded to UT San Antonio; Cornell; and More

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Recent NSF Awards in Proteomics and Protein Research

Title: Acquisition of MALDI TOF/TOF Mass Spectrometer
Principal Investigators: Stephan Bach, Miguel Jose Yacaman, Donald Kurtz, Waldemar Gorski, Harry Jarrett
Sponsor: University of Texas at San Antonio
Start/End Date: Sept. 1, 2011 – Aug. 31, 2014
Amount Awarded to Date: $279,949

Funds acquisition of a MALDI TOF/TOF mass spectrometer for various applications including research into metalloprotein characterization and intracellular location and transcription factor proteomics and protein biomarkers.


Title: Novel Biomarkers that Rapidly Identify Insect Populations that are Efficient Vectors of Circulative Plant Viruses
Principal Investigators: Stewart Gray, Lava Kumar, Michael MacCoss
Sponsor: Cornell University
Start/End Date: July 1, 2011 – June 30, 2014
Amount Awarded to Date: $280,191

Funds an effort to determine whether recently identified protein biomarkers can be used to identify vector competent populations of aphid and whitefly species that transmit circulating viruses affecting a range of staple food crops globally.


Title: Development of a Fluorescent Bar-Coding System for Cell-Based Proteomic Libraries
Principal Investigator: David Colby
Sponsor: University of Delaware
Start/End Date: Aug. 1, 2011 – July 31, 2014
Amount Awarded to Date: $281,593

Funds development of a fluorescent barcode system that will allow for identification of individual proteins. The system will be implemented and tested in a 6,029 member GFP-fusion proteomic yeast library, allowing for single cell measurement of all 6,029 proteins with 200-fold over sampling per minute by flow cytometry.

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.