Recent NSF Awards in Proteomics and Protein Research
Title: Acquisition of MALDI TOF/TOF Mass Spectrometer
Principal Investigators: Stephan Bach, Miguel Jose Yacaman, Donald Kurtz, Waldemar Gorski, Harry Jarrett
Sponsor: University of Texas at San Antonio
Start/End Date: Sept. 1, 2011 – Aug. 31, 2014
Amount Awarded to Date: $279,949
Funds acquisition of a MALDI TOF/TOF mass spectrometer for various applications including research into metalloprotein characterization and intracellular location and transcription factor proteomics and protein biomarkers.
Title: Novel Biomarkers that Rapidly Identify Insect Populations that are Efficient Vectors of Circulative Plant Viruses
Principal Investigators: Stewart Gray, Lava Kumar, Michael MacCoss
Sponsor: Cornell University
Start/End Date: July 1, 2011 – June 30, 2014
Amount Awarded to Date: $280,191
Funds an effort to determine whether recently identified protein biomarkers can be used to identify vector competent populations of aphid and whitefly species that transmit circulating viruses affecting a range of staple food crops globally.
Title: Development of a Fluorescent Bar-Coding System for Cell-Based Proteomic Libraries
Principal Investigator: David Colby
Sponsor: University of Delaware
Start/End Date: Aug. 1, 2011 – July 31, 2014
Amount Awarded to Date: $281,593
Funds development of a fluorescent barcode system that will allow for identification of individual proteins. The system will be implemented and tested in a 6,029 member GFP-fusion proteomic yeast library, allowing for single cell measurement of all 6,029 proteins with 200-fold over sampling per minute by flow cytometry.