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Funding Update: NSF Grants Awarded to University of Minnesota; Northeastern University


Recent NSF Awards in Proteomics and Protein Research

Title: Predicting and Mining Phenome-Genome Association across Species
Principal Investigator: Rui Kuang
Sponsor: University of Minnesota-Twin Cities
Start/End Date: Aug. 1, 2012 – July 31, 2017
Amount Awarded to Date: $83,847

Funds the development of algorithms to predict and interpret associations between genotype and phenotype across a variety of species. Once developed, the methods will be applied to the study of growth phenotypes in Arabidopsis thaliana and in the analysis of phenotypes in several tumor types.

Title: Precise Characterization of Conformational Ensembles
Principal Investigators: Lee Makowski; Dana Brooks; Deniz Erdogmu
Sponsor: Northeastern University
Start/End Date: July 1, 2012 – June 30, 2015
Amount Awarded to Date: $657,070

Funds an effort to characterize the set of all shapes particular proteins can take – their full conformational ensemble – by collecting wide-angle x-ray solution scattering data from the target proteins under a variety of different conditions. This will enable the creation of a map of protein conformational changes that can be used to further functional studies.

The Scan

Follow-Up Data Requests to Biobank Participants Ineffective, Study Finds

An effort to recontact biobank enrollees for additional information reports low participation in a new BMJ Open study.

Study Finds Widespread Transmission of Resistant Bacteria in Vietnam Hospitals

A sequencing study in The Lancet Microbe finds widespread transmission of drug-resistant Escherichia coli, Klebsiella pneumoniae, and Acinetobacter baumannii in two Vietnam ICUs.

Novel Brain Cell Organoids Show Promise for Autism Research

University of Utah researchers report in Nature Communications on their development of brain cell organoids to study SHANK3-related autism.

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.