Recent NSF Awards in Proteomics and Protein Research
Title: Sensitive Dual-mode Microfluidic Optomechanical Analysis of Biomolecules
Principal Investigators: Xudong Fan, Tal Carmon
Sponsor: University of Michigan
Start/End Date: June 1, 2013 – May 31, 2016
Amount Awarded to Date: $370,000
Funds work on using light radiation to cause high frequency mechanical vibrations in a microfluidic optomechanical resonator that can then be used for analyzing biomolecular interactions, including protein-small molecule and protein-protein interactions where both the mass and conformational change of the molecules can be detected.
Title: Increasing the Power of Single-molecule Bio-imaging with Plasmon-enhanced Fluorescence
Principal Investigator: Julie Biteen
Sponsor: University of Michigan
Start/End Date: May 1, 2013 – April 30, 2018
Amount Awarded to Date: $313,000
Funds an effort to couple single-molecule fluorescence microscopy to metal nanoparticle plasmonics to create a non-perturbative method for looking at protein position and dynamics in natural cellular environments.