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Funding Update: NSF Grants Awarded to PhasiQ, Purdue


Recent NSF Awards in Proteomics and Protein Research

Title: Crosstalk-Free Multiplexed Immunoassay of Plasma Biomarkers
Principal Investigator: Arlyne Simon
Sponsor: PhasiQ
Start/End Date: July 1, 2013 – Dec. 31, 2013
Amount Awarded to Date: $149,715

Funds research into a device that can detect protein biomarkers in biological fluids via immunoassays while eliminating false positive signals from nonspecific binding. Also funds development of an initial test panel of protein markers for cardiovascular disease management and drug development.

Title: Gas-Phase Ion Chemistry of Peptide Radical Ions and Applications in Protein Characterization
Principal Investigator: Yu Xia
Sponsor: Purdue University
Start/End Date: July 1, 2013 – June 30, 2016
Amount Awarded to Date: $248,982

Funds research into new mass spectrometry methods and instrumentation for creating peptide radical ions in gas-phase and analyzing their chemical properties.

The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.