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Funding Update: NIH Grants Awarded to Wash U, University of Iowa, and More

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NIH Grants in Proteomics, June 26 to Sept. 14, Part 3 of 3 (Click for part 1 and part 2.)

Project Title: Resolving the Role of Nicotine-Mediated Phosphorylation on Pancreatic Fibrosis
Contact Principal Investigator: Joao Paulo
Organization Name: Harvard Medical School
Project Start Date: Sept. 16, 2013
Project End Date: Aug. 31, 2018
FY Total Cost: $127,831


Project Title: Integrated Approach to Protein Biomarker Identification in Huntington Disease
Contact Principal Investigator: Jane Paulsen
Organization Name: University of Iowa
Project Start Date: Sept. 25, 2013
Project End Date: Aug. 31, 2016
FY Total Cost: $74,745


Project Title: Integrated Approach to Protein Biomarker Identification in Huntington Disease
Contact Principal Investigator: Jane Paulsen
Organization Name: University of Iowa
Project Start Date: Sept. 25, 2013
Project End Date: Aug. 31, 2016
FY Total Cost: $548,273


Project Title: How Bacteria Corrupt the Host Vesicular Trafficking: Interfering with Host Snares
Contact Principal Investigator: Fabienne Paumet
Organization Name: Thomas Jefferson University
Project Start Date: July 1, 2009
Project End Date: July 31, 2015
FY Total Cost: $387,500


Project Title: Large-Scale High-Confidence Binary Protein Interaction Network for Drosophila
Contact Principal Investigator: Norbert Perrimon
Organization Name: Harvard Medical School
Project Start Date: Sept. 4, 2013
Project End Date: June 30, 2018
FY Total Cost: $837,691


Project Title: Endothelial Mechanisms of Impaired Lung Gas Exchange by HIV
Contact Principal Investigator: Irina Petrache
Organization Name: Indiana University-Purdue University At Indianapolis
Project Start Date: Sept. 11, 2014
Project End Date: Aug. 31, 2015
FY Total Cost: $683,614


Project Title: Preservation of Dried Plasma Spots for Downstream Proteomic Applications
Contact Principal Investigator: Konstantinos Petritis
Organization Name: Phoenix Children's Hospital
Project Start Date: Sept. 1, 2014
Project End Date: Aug. 31, 2017
FY Total Cost: $285,534


Project Title: Personal Omics Profiling of the Progression to Diabetes Mellitus Type 2
Contact Principal Investigator: Brian Piening
Organization Name: Stanford University
Project Start Date: Sept. 1, 2014
Project End Date: Aug. 31, 2016
FY Total Cost: $51,530


Project Title: Proteomics Core
Contact Principal Investigator: Scott Pomeroy
Organization Name: Children's Hospital Corporation
Project Start Date: NA
Project End Date: NA
FY Total Cost: $150,213


Project Title: Role of Ctyokines and APOl-1 in the Pathogenesis of Childhood HIV Associated Neph
Contact Principal Investigator: Patricio Ray
Organization Name: Children's Research Institute
Project Start Date: Aug. 1, 2014
Project End Date: June 30, 2018
FY Total Cost: $430,000


Project Title: Quantitative Analysis of LC-MS Data for Peptide and Glycan Biomarker Discovery
Contact Principal Investigator: Habtom Ressom
Organization Name: Georgetown University
Project Start Date: Aug. 1, 2010
Project End Date: July 31, 2015
FY Total Cost: $265,939


Project Title: Investigation of Electrolyte Homeostasis via Quantitative Proteomics
Contact Principal Investigator: Jesse Rinehart
Organization Name: Yale University
Project Start Date: Sept. 2, 2010
Project End Date: Aug. 31, 2015
FY Total Cost: $154,332


Project Title: Mass Spectrometry Core
Contact Principal Investigator: Jackson Roberts
Organization Name: Vanderbilt University
Project Start Date: NA
Project End Date: NA
FY Total Cost: $69,908


Project Title: Administrative & Biostatistics Core
Contact Principal Investigator: Jackson Roberts
Organization Name: Vanderbilt University
Project Start Date: NA
Project End Date: NA
FY Total Cost: $69,727


Project Title: The Role of Mercury Exposures in Disrupting Central Tolerance
Contact Principal Investigator: Allen Rosenspire
Organization Name: Wayne State University
Project Start Date: Aug. 1, 2014
Project End Date: July 31, 2016
FY Total Cost: $228,000


Project Title: Discovery & Validation of Biomarkers of Kidney Pathology
Contact Principal Investigator: Brad Rovin
Organization Name: Ohio State University
Project Start Date: Sept. 20, 2013
Project End Date: Aug. 31, 2018
FY Total Cost: $397,601


Project Title: Protein Biosensor Arrays Based on Nanomaterials
Contact Principal Investigator: James Rusling
Organization Name: University of Connecticut Storrs
Project Start Date: Sept. 15, 2011
Project End Date: Aug. 31, 2015
FY Total Cost: $335,574


Project Title: Modified Nucleotide Cofactors and the Interaction of the RNAome with the Proteome
Contact Principal Investigator: Gary Ruvkun
Organization Name: Massachusetts General Hospital
Project Start Date: Sept. 30, 2011
Project End Date: Aug. 31, 2015
FY Total Cost: $348,000


Project Title: The Discovery of Human Peptide Encoding Genes
Contact Principal Investigator: Alan Saghatelian
Organization Name: Salk Institute for Biological Studies
Project Start Date: Sept. 21, 2012
Project End Date: Aug. 31, 2016
FY Total Cost: $432,405


Project Title: Proteomics and Genomics Core
Contact Principal Investigator: Daniel Salomon
Organization Name: University of Miami School of Medicine
Project Start Date: NA
Project End Date: NA
FY Total Cost: $290,545


Project Title: The Genetic and Neuroanatomical Origin of Social Behavior
Contact Principal Investigator: Rodney Samaco
Organization Name: Baylor College of Medicine
Project Start Date: Sept. 20, 2011
Project End Date: Aug. 31, 2016
FY Total Cost: $391,249


Project Title: The Genetic and Neuroanatomical Origin of Social Behavior
Contact Principal Investigator: Rodney Samaco
Organization Name: Baylor College of Medicine
Project Start Date: Sept. 20, 2011
Project End Date: Aug. 31, 2016
FY Total Cost: $1


Project Title: The Role of the First Mammalian N-Term. Methyltransferase, NRMT, in Tumorigenesis
Contact Principal Investigator: Christine Schaner-Tooley
Organization Name: University of Louisville
Project Start Date: Sept. 5, 2011
Project End Date: Aug. 31, 2015
FY Total Cost: $227,037


Project Title: The Role of Aquaporin-0 in Lens Development and Aging
Contact Principal Investigator: Kevin Schey
Organization Name: Vanderbilt University
Project Start Date: May 1, 2001
Project End Date: July 31, 2016
FY Total Cost: $288,443


Project Title: Immune Monitoring
Contact Principal Investigator: Gregory Sempowski
Organization Name: Duke University
Project Start Date: NA
Project End Date: NA
FY Total Cost: $74,308


Project Title: Host Response Monitoring
Contact Principal Investigator: Gregory Sempowski
Organization Name: Henry M. Jackson Foundation
Project Start Date: NA
Project End Date: NA
FY Total Cost: $227,175


Project Title: Molecular Pathophysiology of Retinal Degeneration in Bardet-Biedl Syndrome
Contact Principal Investigator: Seongjin Seo
Organization Name: University of Iowa
Project Start Date: Sept. 1, 2012
Project End Date: Aug. 31, 2016
FY Total Cost: $372,659


Project Title: Molecular Mechanisms of Post-Translational Targeting of Tail-Anchored Proteins.
Contact Principal Investigator: Shu-Ou Shan
Organization Name: California Institute of Technology
Project Start Date: Aug. 1, 2014
Project End Date: July 31, 2018
FY Total Cost: $355,846


Project Title: Human Cytomegalovirus-Induced Alterations to Cell-Surface Adhesion Proteins
Contact Principal Investigator: Thomas Shenk
Organization Name: Princeton University
Project Start Date: Aug. 1, 2014
Project End Date: July 31, 2015
FY Total Cost: $399,362


Project Title: Salivary Biomarker Panel for Measuring and Predicting Traumatic Stress Reactions
Contact Principal Investigator: Vivek Shetty
Organization Name: University of California Los Angeles
Project Start Date: Sept. 1, 2012
Project End Date: Aug. 31, 2017
FY Total Cost: $679,100


Project Title: EPH-Receptor Signaling in Lens Development and Aging
Contact Principal Investigator: Alan Shiels
Organization Name: Washington University
Project Start Date: Aug. 1, 2013
Project End Date: July 31, 2018
FY Total Cost: $338,802


Project Title: Center for Application of Advanced Clinical Proteomic Technologies for Cancer
Contact Principal Investigator: Richard Smith
Organization Name: Battelle Pacific Northwest Laboratories
Project Start Date: Aug. 26, 2011
Project End Date: July 31, 2016
FY Total Cost: $2,790,034


Project Title: Longitudinal Multiomics Microbial Profiling in Healthy and Disease Individuals
Contact Principal Investigator: Michael Snyder
Organization Name: Stanford University
Project Start Date: Sept. 6, 2013
Project End Date: Aug. 31, 2016
FY Total Cost: $1,099,529


Project Title: Longitudinal Multiomics Microbial Profiling in Healthy and Disease Individuals
Contact Principal Investigator: Michael Snyder
Organization Name: Stanford University
Project Start Date: Sept. 6, 2013
Project End Date: Aug. 31, 2016
FY Total Cost: $1,400,000


Project Title: Camelid Antibodies as Sensitive Proteomics Tools for Developmental Studies
Contact Principal Investigator: Sergei Sokol
Organization Name: Icahn School of Medicine at Mount Sinai
Project Start Date: Sept. 8, 2014
Project End Date: Aug. 31, 2016
FY Total Cost: $254,250


Project Title: Pharmaco Response Signatures and Disease Mechanism
Contact Principal Investigator: Peter Sorger
Organization Name: Harvard Medical School
Project Start Date: Sept. 10, 2014
Project End Date: June 30, 2020
FY Total Cost: $2,145,458


Project Title: Identification of Ovarian Cancer Plasma Biomarkers
Contact Principal Investigator: David Speicher
Organization Name: Wistar Institute
Project Start Date: Dec. 1, 2007
Project End Date: June 30, 2019
FY Total Cost: $440,659


Project Title: Proteomics
Contact Principal Investigator: Bruce Stillman
Organization Name: Cold Spring Harbor Laboratory
Project Start Date: NA
Project End Date: NA
FY Total Cost: $344,981


Project Title: Developing Novel Peptide Arrays for Epigenetic Research
Contact Principal Investigator: Zu-Wen Sun
Organization Name: Epicypher
Project Start Date: July 7, 2014
Project End Date: July 6, 2015
FY Total Cost: $220,206


Project Title: Development of Molecular Probes for Biomedical Applications
Contact Principal Investigator: Weihong Tan
Organization Name: University of Florida
Project Start Date: March 1, 2007
Project End Date: June 30, 2017
FY Total Cost: $156,243


Project Title: Development of Molecular Probes for Biomedical Applications
Contact Principal Investigator: Weihong Tan
Organization Name: University of Florida
Project Start Date: March 1, 2007
Project End Date: June 30, 2017
FY Total Cost: $163,900


Project Title: VMS1 is a Novel Protein Critical for Mitochondrial Maintenance
Contact Principal Investigator: Eric Taylor
Organization Name: University of Iowa
Project Start Date: Sept. 8, 2012
Project End Date: Aug. 31, 2015
FY Total Cost: $244,019


Project Title: Mast Cells
Contact Principal Investigator: Susan Taylor
Organization Name: University of California San Diego
Project Start Date: NA
Project End Date: NA
FY Total Cost: $464,580


Project Title: Shifts in the Gastrointestinal Metabolome During Clostridium Difficile Infection
Contact Principal Investigator: Casey Theriot
Organization Name: University of Michigan
Project Start Date: Sept. 30, 2013
Project End Date: Aug. 31, 2017
FY Total Cost: $123,747


Project Title: Identification of Citrullinated Biomarkers of Inflammatory Disease and Cancer
Contact Principal Investigator: Paul Thompson
Organization Name: University of Massachusetts Medical School Worcester
Project Start Date: May 1, 2014
Project End Date: Jan. 31, 2018
FY Total Cost: $559,848


Project Title: Spatially-Resolved Proteomic Mapping of Living Cells
Contact Principal Investigator: Alice Ting
Organization Name: Massachusetts Institute of Technology
Project Start Date: Sept. 23, 2013
Project End Date: July 31, 2018
FY Total Cost: $601,805


Project Title: PTTQ1 Regulates Anti-Cancer Drug Response
Contact Principal Investigator: Yunguang Tong
Organization Name: Cedars-Sinai Medical Center
Project Start Date: Sept. 1, 2012
Project End Date: Aug. 31, 2015
FY Total Cost: $241,530


Project Title: Axl Receptor Signaling in MPNST; Potential Node for Therapy
Contact Principal Investigator: Keila Torres
Organization Name: University Of Texas MD Anderson Cancer Center
Project Start Date: Sept. 7, 2012
Project End Date: Aug. 31, 2017
FY Total Cost: $170,618


Project Title: Proteomics Core
Contact Principal Investigator: Reid Townsend
Organization Name: Washington University
Project Start Date: NA
Project End Date: NA
FY Total Cost: $143,963


Project Title: Cancer Proteome Center at Washington University, University of North Carolina
Contact Principal Investigator: Reid Townsend
Organization Name: Washington University
Project Start Date: Aug. 22, 2011
Project End Date: July 31, 2016
FY Total Cost: $2,197,655


Project Title: Genetic and Functional Interaction Between the Proteasome and the Primary Cilium
Contact Principal Investigator: I-Chun Tsai
Organization Name: Duke University
Project Start Date: Sept. 1, 2012
Project End Date: Aug. 31, 2015
FY Total Cost: $63,122


Project Title: CRT and Mitochondrial Function and Proteome Post-Translational Modifications
Contact Principal Investigator: Jennifer Van Eyk
Organization Name: Johns Hopkins University
Project Start Date: NA
Project End Date: NA
FY Total Cost: $427,504


Project Title: How Proinflammatory Cytokines Block T Cell Death in Vivo
Contact Principal Investigator: Anthony Vella
Organization Name: University of Connecticut School of Medicine/Dentistry
Project Start Date: July 1, 1999
Project End Date: Feb. 28, 2017
FY Total Cost: $57,800


Project Title: Thioredoxin Signaling and Pulmonary Development During Perina......
Contact Principal Investigator: Peter Vitiello
Organization Name: Sanford Research
Project Start Date: NA
Project End Date: NA
FY Total Cost: $297,472


Project Title: Mechanisms of Lipid Droplet Protein Targeting
Contact Principal Investigator: Tobias Walther
Organization Name: Harvard School of Public Health
Project Start Date: Sept. 30, 2011
Project End Date: Aug. 31, 2016
FY Total Cost: $403,750


Project Title: Mechanisms of Glucose Mediated Cardiac Mitochondrial Dysfunction
Contact Principal Investigator: Adam Wende
Organization Name: University of Alabama at Birmingham
Project Start Date: Aug. 2, 2013
Project End Date: July 31, 2016
FY Total Cost: $144,059


Project Title: Mechanisms of Glucose Mediated Cardiac Mitochondrial Dysfunction
Contact Principal Investigator: Adam Wende
Organization Name: University of Alabama at Birmingham
Project Start Date: Aug. 2, 2013
Project End Date: July 31, 2016
FY Total Cost: $244,020


Project Title: Exploring the Venom Repertoire of Parasitoids
Contact Principal Investigator: John Werren
Organization Name: University of Rochester
Project Start Date: Aug. 1, 2011
Project End Date: July 31, 2015
FY Total Cost: $339,181


Project Title: Exploring the Venom Repertoire of Parasitoids
Contact Principal Investigator: John Werren
Organization Name: University of Rochester
Project Start Date: Aug. 1, 2011
Project End Date: July 31, 2015
FY Total Cost: $4,326


Project Title: Mechanisms of LRRK2 Mediated Neurotoxicity
Contact Principal Investigator: Andrew West
Organization Name: University of Alabama at Birmingham
Project Start Date: Sept. 1, 2010
Project End Date: Aug. 31, 2015
FY Total Cost: $310,918


Project Title: LRRK2 and Other Novel Exosome Proteins in Parkinson's Disease
Contact Principal Investigator: Andrew West
Organization Name: University of Alabama at Birmingham
Project Start Date: Aug. 25, 2014
Project End Date: Dec. 31, 2015
FY Total Cost: $29,135


Project Title: Core E: Novel Target Discovery and Assay
Contact Principal Investigator: Julian Whitelegge
Organization Name: University of California San Diego
Project Start Date: NA
Project End Date: NA
FY Total Cost: $216,677


Project Title: Piezoelectric Pipetting for High Density Nucleic Acid Programmable Protein Arrays
Contact Principal Investigator: Peter Wiktor
Organization Name: Engineering Arts
Project Start Date: Sept. 15, 2010
Project End Date: July 31, 2015
FY Total Cost: $599,557


Project Title: Development of Single Particle Analyzer of Mass and Mobility (Spamm)
Contact Principal Investigator: Evan Williams
Organization Name: University of California Berkeley
Project Start Date: July 1, 2011
Project End Date: June 30, 2015
FY Total Cost: $229,247


Project Title: Targeting Endogenous Signaling Pathways to Ameliorate Systemic Amyloidoses
Contact Principal Investigator: Rockland Wiseman
Organization Name: Scripps Research Institute
Project Start Date: Sept. 8, 2014
Project End Date: June 30, 2018
FY Total Cost: $221,506


Project Title: Identification of Microbiome Proteins Associated with IBD
Contact Principal Investigator: Dennis Wolan
Organization Name: Scripps Research Institute
Project Start Date: Sept. 1, 2014
Project End Date: Aug. 31, 2016
FY Total Cost: $206,081


Project Title: High-Specificity Affinity Reagents for N-Glycosylation Site Mapping and Glycomics
Contact Principal Investigator: Robert Woods
Organization Name: Glycosensors and Diagnostics
Project Start Date: Sept. 1, 2009
Project End Date: Aug. 31, 2016
FY Total Cost: $589,209


Project Title: Biopolymers & Proteomics
Contact Principal Investigator: Michael Yaffe
Organization Name: Massachusetts Institute of Technology
Project Start Date: NA
Project End Date: NA
FY Total Cost: $197,910


Project Title: Quantitative Proteome Analysis of Brain Development
Contact Principal Investigator: John Yates
Organization Name: Scripps Research Institute
Project Start Date: April 1, 2003
Project End Date: July 31, 2018
FY Total Cost: $560,456


Project Title: Proteogenetics
Contact Principal Investigator: John Yates
Organization Name: Scripps Research Institute
Project Start Date: Aug. 1, 2013
Project End Date: July 31, 2015
FY Total Cost: $510,801


Project Title: Human Skeletal Muscle Proteome and Phosphoproteome in Obesity and Type 2 Diabetes
Contact Principal Investigator: Zhengping Yi
Organization Name: Wayne State University
Project Start Date: July 1, 2008
Project End Date: April 30, 2018
FY Total Cost: $267,412


Project Title: Autoantibodies to Tumor-Associated Antigens as Diagnostic Biomarkers in Liver Cancer
Contact Principal Investigator: Jianying Zhang
Organization Name: University of Texas El Paso
Project Start Date: Aug. 5, 2011
Project End Date: July 31, 2015
FY Total Cost: $253,776


Project Title: Protein Markers to T1D Progression
Contact Principal Investigator: Qibin Zhang
Organization Name: University of North Carolina Greensboro
Project Start Date: Sept. 5, 2013
Project End Date: Aug. 31, 2015
FY Total Cost: $388,054


Project Title: Monospecific Monoclonal Antibodies against Human Transcription Factors
Contact Principal Investigator: Heng Zhu
Organization Name: Johns Hopkins University
Project Start Date: Sept. 26, 2011
Project End Date: July 31, 2016
FY Total Cost: $1,000,000


Project Title: Monospecific Monoclonal Antibodies against Human Transcription Factors
Contact Principal Investigator: Heng Zhu
Organization Name: Johns Hopkins University
Project Start Date: Sept. 26, 2011
Project End Date: July 31, 2016
FY Total Cost: $1,892,054


Project Title: Protein Core
Contact Principal Investigator: Gerard Zurawski
Organization Name: Baylor Research Institute
Project Start Date: NA
Project End Date: NA
FY Total Cost: $144,535

The Scan

Foxtail Millet Pangenome, Graph-Based Reference Genome

Researchers in Nature Genetics described their generation of a foxtail millet pangenome, which they say can help in crop trait improvement.

Protein Length Distribution Consistent Across Species

An analysis in Genome Biology compares the lengths of proteins across more than 2,300 species, finding similar length distributions.

Novel Genetic Loci Linked to Insulin Resistance in New Study

A team reports in Nature Genetics that it used glucose challenge test data to home in on candidate genes involved in GLUT4 expression or trafficking.

RNA Editing in Octopuses Seems to Help Acclimation to Shifts in Water Temperature

A paper in Cell reports that octopuses use RNA editing to help them adjust to different water temperatures.